INT147225

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (Slc22a8) plasma membrane (Slc22a8)
Slc22a8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
methotrexate 14 99.02 Very High Very High Very High
cINOD 2 46.56 Quite Low
Analgesic 1 10.00 Low Low
pulpitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 46.00 Quite Low
Injury 1 5.00 Very Low Very Low Very Low
Pulpitis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicated that celecoxib inhibited the secretion of methotrexate via hOAT3, which suggested that celecoxib was a substrate of hOAT3.
Positive_regulation (substrate) of hOAT3 associated with methotrexate
1) Confidence 0.49 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20478302 Disease Relevance 0 Pain Relevance 0.38
Patients undergoing single-visit RoCT reported a higher frequency of painkiller use and swelling, but the results for swelling were not significantly different between the two groups.
Positive_regulation (undergoing) of RoCT
2) Confidence 0.37 Published 2007 Journal Cochrane Database Syst Rev Section Body Doc Link 17943848 Disease Relevance 0 Pain Relevance 0

General Comments

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