INT147361

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk9) signal transduction (Tnfrsf10b) mitochondrion (Mapk9)
nucleus (Mapk9) kinase activity (Mapk9) transcription factor binding (Mapk9)
Mapk9 (Mus musculus)
Tnfrsf10b (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 1 88.48 High High
Nerve growth factor 1 58.84 Quite High
Disease Link Frequency Relevance Heat
Death 1 100.00 Very High Very High Very High
Apoptosis 3 99.08 Very High Very High Very High
Colon Cancer 4 93.80 High High
INFLAMMATION 1 88.28 High High
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DIM-C-pPhOCH(3) also activated the extrinsic apoptosis pathway through increased phosphorylation of c-jun N-terminal kinase which, in turn, activated C/EBP homologous transcription factor (CHOP) and death receptor 5 (DR5).
c-jun N-terminal kinase Positive_regulation (activated) of DR5 associated with apoptosis and death
1) Confidence 0.40 Published 2008 Journal Mol. Carcinog. Section Abstract Doc Link 17957723 Disease Relevance 0.76 Pain Relevance 0.12

General Comments

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