INT14738

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Context Info
Confidence 0.41
First Reported 1991
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (TGFB1) enzyme binding (TGFB1) embryo development (TGFB1)
cytoplasm (TGFB1) extracellular space (TGFB1) extracellular region (TGFB1)
Anatomy Link Frequency
dermis 2
TGFB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 70.36 Quite High
fibrosis 1 57.88 Quite High
Chronic pancreatitis 1 49.32 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Syndrome 4 90.40 High High
Myalgia 2 89.84 High High
Eosinophilia 2 89.52 High High
Fasciitis 3 88.20 High High
Fibrosis 1 57.88 Quite High
Pancreatitis 1 49.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The immunohistochemical studies demonstrated increased deposition of TGF-beta, type VI collagen, and fibronectin epitopes in the extracellular matrix of the fascia in comparison to the adjacent dermis in the same specimens.
Negative_regulation (deposition) of Regulation (epitopes) of TGF-beta in dermis
1) Confidence 0.41 Published 1991 Journal J. Invest. Dermatol. Section Abstract Doc Link 1702819 Disease Relevance 0.75 Pain Relevance 0.03
Thus, serine protease inhibitors act on hPFCs to diminish the effects of PDGF on proliferation and the effects of TGF-beta1 on collagen synthesis.
Negative_regulation (diminish) of Regulation (effects) of TGF-beta1
2) Confidence 0.10 Published 2001 Journal Pancreas Section Abstract Doc Link 11291936 Disease Relevance 0.06 Pain Relevance 0.06

General Comments

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