INT147386

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (TRPV1, TRPV2) plasma membrane (TRPV1, TRPV2) cytosol (TRPV1)
intracellular (TRPV2) cytoplasm (TRPV2) lipid metabolic process (TRPV1)
TRPV1 (Homo sapiens)
TRPV2 (Homo sapiens)
Pain Link Frequency Relevance Heat
vanilloid receptor subtype 1 1 87.04 High High
qutenza 1 62.16 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we show that replacement of the TRP domain of TRPV1 with the cognate region of TRPV channels (TRPV2-TRPV6) did not affect receptor assembly and trafficking to the cell surface, although those receptors containing the TRP domain of the distantly related TRPV5 and TRPV6 did not display ion channel activity.
Neg (not) Regulation (affect) of TRPV1 Binding (replacement) of TRPV2
1) Confidence 0.45 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17959807 Disease Relevance 0 Pain Relevance 0.15

General Comments

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