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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.45

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cell proliferation (NDP) signal transduction (NDP) extracellular space (NDP)
extracellular region (NDP) cell-cell signaling (NDP)
Anatomy Link Frequency
melanocytes 2
NDP (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 5 95.32 Very High Very High Very High
agonist 1 94.40 High High
Disease Link Frequency Relevance Heat
Sprains And Strains 2 99.24 Very High Very High Very High
Skin Cancer 2 69.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of mRNA expression and protein levels of the major pigmentation markers following NDP-MSH treatment distinguished the enzyme dopachrome tautomerase as preferentially upregulated in cocultures of WT strains, with negligible or a much reduced response in melanocytes with RHC variant alleles.
Positive_regulation (upregulated) of Transcription (expression) of NDP-MSH in melanocytes associated with sprains and strains
1) Confidence 0.20 Published 2008 Journal J. Cell. Physiol. Section Abstract Doc Link 17960564 Disease Relevance 0.27 Pain Relevance 0.45

General Comments

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