INT147415

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.97
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Igf1r)
Anatomy Link Frequency
hindlimb 1
hippocampus 1
Igf1r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 3 99.90 Very High Very High Very High
fluoxetine 10 98.52 Very High Very High Very High
antidepressant 2 77.24 Quite High
Mechanotransduction 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Codeine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 7 99.58 Very High Very High Very High
Stress 22 87.48 High High
Cognitive Disorder 3 86.24 High High
Injury 10 40.44 Quite Low
Wound Healing 1 28.76 Quite Low
Cicatrix 7 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Body Weight 5 5.00 Very Low Very Low Very Low
Hematoma 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute FLX administration decreased IGF-1 mRNA levels in the FC and hippocampus and increased IGF-1R levels in the FC.
Positive_regulation (increased) of IGF-1R in hippocampus associated with urological neuroanatomy, hippocampus and fluoxetine
1) Confidence 0.43 Published 2008 Journal Eur Neuropsychopharmacol Section Abstract Doc Link 17961991 Disease Relevance 0.72 Pain Relevance 1.09
Furthermore, levels of IGF-receptor were significantly increased in tissues from hindlimb unloaded animals treated with IGF-I.


Positive_regulation (increased) of IGF-receptor in hindlimb
2) Confidence 0.08 Published 2007 Journal BMC Physiol Section Abstract Doc Link PMC1851714 Disease Relevance 0.25 Pain Relevance 0

General Comments

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