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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.12
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADCYAP1, NFKB1) nucleoplasm (NFKB1) mitochondrion (NFKB1)
cytoplasm (NFKB1) cell-cell signaling (ADCYAP1) cytosol (NFKB1)
Anatomy Link Frequency
ADCYAP1 (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 11 99.84 Very High Very High Very High
Inflammation 3 97.76 Very High Very High Very High
cytokine 2 89.52 High High
Neuropeptide 2 75.00 Quite High
Inflammatory response 1 75.00 Quite High
Pain 5 55.84 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 11 99.84 Very High Very High Very High
INFLAMMATION 4 97.76 Very High Very High Very High
Apoptosis 1 77.20 Quite High
Nociception 1 74.64 Quite High
Disease 1 57.68 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The change of PACAP-mediated anti-inflammatory pattern was associated with altered activation of NF-kappaB: compared with LPS alone, a combination of LPS and PACAP had no effect on NF-kappaB p65 nuclear translocation in CP PBMC, whereas NF-kappaB was significantly decreased in donor PBMC.
PACAP Neg (no) Regulation (effect) of Localization (translocation) of NF-kappaB in PBMC associated with inflammation and chronic pancreatitis
1) Confidence 0.47 Published 2008 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17962362 Disease Relevance 1.12 Pain Relevance 1.15

General Comments

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