INT147453

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.49
Pain Relevance 2.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADCYAP1) extracellular region (ADCYAP1) cell-cell signaling (ADCYAP1)
Anatomy Link Frequency
PBMC 4
platelet 2
ADCYAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 22 99.48 Very High Very High Very High
Pain 10 87.04 High High
Inflammation 6 86.32 High High
cytokine 4 78.12 Quite High
Neuropeptide 4 75.00 Quite High
Inflammatory response 2 75.00 Quite High
agonist 8 70.04 Quite High
Serotonin 13 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 22 99.48 Very High Very High Very High
Thrombocytopenia 4 99.48 Very High Very High Very High
Nociception 2 99.22 Very High Very High Very High
Apoptosis 2 98.84 Very High Very High Very High
Hemorrhage 23 88.28 High High
Hypogonadotropic Hypogonadism 1 86.64 High High
INFLAMMATION 8 84.12 Quite High
Vomiting 1 83.12 Quite High
Diarrhoea 1 82.72 Quite High
Syndrome 20 81.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to laser-capture microdissection and coculture experiments, PBMC also contributed to generation of a PACAP-rich intrapancreatic environment by upregulating PACAP expression in macrophages encountering apoptotic pancreatic acini.
Positive_regulation (upregulating) of Gene_expression (expression) of PACAP in PBMC associated with apoptosis
1) Confidence 0.69 Published 2008 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17962362 Disease Relevance 0.92 Pain Relevance 1.07
The nociceptive status of CP patients correlated with pancreatic PACAP levels and with IL-10 bias of PACAP-exposed CP PBMC.
Positive_regulation (pancreatic) of Gene_expression (levels) of PACAP in PBMC associated with nociception and chronic pancreatitis
2) Confidence 0.44 Published 2008 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17962362 Disease Relevance 0.95 Pain Relevance 1.00
Patients with PACAP overexpression have a mild thrombocytopenia, a normal platelet survival, relatively small platelets and their bone marrow examination reveals almost no mature megakaryocytes.
Positive_regulation (overexpression) of Gene_expression (overexpression) of PACAP in platelet associated with thrombocytopenia
3) Confidence 0.38 Published 2007 Journal Eur J Pediatr Section Body Doc Link PMC2042511 Disease Relevance 1.62 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox