INT147464

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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 15.18
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptprc)
Anatomy Link Frequency
visceral 1
margins 1
thyroid 1
immune system 1
Ptprc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
abdominal pain 18 95.68 Very High Very High Very High
imagery 35 95.32 Very High Very High Very High
Analgesic 1 92.32 High High
Pain 8 90.16 High High
Crohn's disease 6 85.44 High High
Inflammation 1 78.00 Quite High
antinociception 1 76.72 Quite High
colic 12 64.24 Quite High
cva 12 62.32 Quite High
ischemia 5 57.56 Quite High
Disease Link Frequency Relevance Heat
Hemangioma 336 100.00 Very High Very High Very High
Recurrence 165 100.00 Very High Very High Very High
Malignant Neoplastic Disease 64 100.00 Very High Very High Very High
Cancer 330 99.86 Very High Very High Very High
Metastasis 82 99.70 Very High Very High Very High
Injury 3 99.60 Very High Very High Very High
Abscess 1 98.60 Very High Very High Very High
Rectal Cancer 180 98.48 Very High Very High Very High
Hypersplenism 12 98.24 Very High Very High Very High
Splenomegaly 18 97.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, the association of LCA with other cancer types may also be a result of making an incidental diagnosis of LCA during extensive radiological imaging for other diseases, given the largely asymptomatic presentation of these tumours [22].
LCA Binding (association) of associated with cancer, hemangioma, disease and imagery
1) Confidence 0.36 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 2.23 Pain Relevance 0.08
The other cancer types associated with LCA include: thyroid, colorectal, renal, pancreatic, hematologic (lymphoma), ovarian, and testicular cancer [10,13,18,20,21].
LCA Binding (associated) of in thyroid associated with lymphatic system cancer, hemangioma, cancer and testicular cancer
2) Confidence 0.36 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 2.13 Pain Relevance 0.07
Indeed, immune system dysregulation may explain the association of LCA with other cancer types.
LCA Binding (association) of in immune system associated with cancer and hemangioma
3) Confidence 0.36 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 2.16 Pain Relevance 0.12
Neoplasia of these cells results in the formation of LCA, which exhibit histologic and molecular features consistent with both these epithelial and histiocytic cell types [17,18].
LCA Binding (formation) of associated with hemangioma and cancer
4) Confidence 0.32 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 1.85 Pain Relevance 0.15
Although first described as benign, LCA has recently been shown to exhibit malignant potential [11,12] and may also be associated with other visceral malignancies [13].
LCA Binding (associated) of in visceral associated with malignant neoplastic disease and hemangioma
5) Confidence 0.27 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 1.71 Pain Relevance 0.18
Although the vast majority of LCAs are benign, their differential diagnosis must include both primary and secondary malignancy, given LCA's association with other cancer types as well as their uncertain malignant potential.
LCA Binding (association) of associated with malignant neoplastic disease, cancer and hemangioma
6) Confidence 0.27 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 1.29 Pain Relevance 0
The overall survival was the same for both treatment groups but the local recurrence rate was lower and the morbidity less for preoperative RT.
RT Binding (less) of associated with recurrence
7) Confidence 0.26 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.44 Pain Relevance 0.06
Should preoperative RT be recommended for adjuvant treatment in resectable rectal cancer?
RT Binding (recommended) of associated with rectal cancer
8) Confidence 0.26 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.49 Pain Relevance 0
Preoperative RT was better in reducing local recurrence rates and was associated with lower morbidity.
RT Binding (associated) of associated with recurrence
9) Confidence 0.26 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.47 Pain Relevance 0
Preoperative RT with surgery at different intervals
RT Binding (intervals) of
10) Confidence 0.26 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.49 Pain Relevance 0
The CCCG search yielded 19 trials of preoperative RT which included five trials not included in our review: two trials using preoperative plus postoperative RT [15,31], one trial including patients with metastatic disease [14], another combining RT with 5-fluorouracil (5-FU) administration [33] and a Japanese trial published in 1989.
RT Binding (combining) of associated with metastasis
11) Confidence 0.26 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 1.00 Pain Relevance 0
We observed (1) increases in pulp CRF-R immunoreactivity after injury, (2) increased CRF-R immunoreactivity expressed in 3 distinct zones in relation to the injury, and (3) increased CD45 and END immunoreactivity in regions surrounding the pulpal abscess.
CD45 Binding (immunoreactivity) of associated with injury and abscess
12) Confidence 0.26 Published 2007 Journal J Endod Section Abstract Doc Link 17963955 Disease Relevance 0.45 Pain Relevance 0.30
However, this modality only reduces the number of positive postoperative margins after radical prostatectomy (RP), but without any influence on overall patient survival.15 The mechanism whereby HT and RT interact has been studied in vivo in animal models.
RT Binding (interact) of in margins
13) Confidence 0.01 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004567 Disease Relevance 0.48 Pain Relevance 0

General Comments

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