INT147473

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Context Info
Confidence 0.74
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nfe2l2, Hmox1) endoplasmic reticulum (Hmox1) enzyme binding (Hmox1)
DNA binding (Nfe2l2) signal transducer activity (Hmox1) cytoplasm (Nfe2l2)
Nfe2l2 (Mus musculus)
Hmox1 (Mus musculus)
Pain Link Frequency Relevance Heat
Antinociceptive 3 99.52 Very High Very High Very High
IPN 3 91.84 High High
Inflammation 3 25.00 Low Low
Pain 3 25.00 Low Low
nociceptor 2 25.00 Low Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 96.52 Very High Very High Very High
Inflammatory Pain 3 75.00 Quite High
Nociception 2 54.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, Nrf2-mediated HO-1 expression induced an antinociceptive effect at peripheral sites.
Nrf2 Positive_regulation (mediated) of Gene_expression (expression) of HO-1 associated with antinociceptive
1) Confidence 0.74 Published 2008 Journal Pain Section Abstract Doc Link 17964723 Disease Relevance 0.49 Pain Relevance 0.39

General Comments

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