INT147521

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ugt1a1) enzyme binding (Ugt1a1)
Anatomy Link Frequency
CAR 2
Ugt1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 87.52 High High
Paracetamol 3 72.64 Quite High
Inflammation 41 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Periodontitis 30 100.00 Very High Very High Very High
Alveolar Bone Loss 7 50.48 Quite High
Hypercalcemia 2 26.20 Quite Low
INFLAMMATION 44 5.00 Very Low Very Low Very Low
Periodontal Disease 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results indicate that nutritional status may gender-specifically influence the expression and activation of CAR and PPARalpha in liver cell nuclei, and this effect appears to be associated with alterations in UGT1A1 and UGT1A6 expression.
Regulation (alterations) of Gene_expression (expression) of UGT1A1 in CAR
1) Confidence 0.23 Published 2008 Journal Drug Metab. Dispos. Section Abstract Doc Link 17967931 Disease Relevance 0 Pain Relevance 0.26
Hypericum treatment significantly prevented the periodontitis-mediated NF-kB p65 expression (Figure 3b, b1).
Regulation (periodontitis) of Gene_expression (expression) of b1 associated with periodontitis
2) Confidence 0.09 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.39 Pain Relevance 0

General Comments

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