INT147540

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Context Info
Confidence 0.20
First Reported 2007
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 9
Disease Relevance 3.58
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Si) plasma membrane (Si) carbohydrate metabolic process (Si)
Anatomy Link Frequency
ileum 1
jejunum 1
duodenum 1
Si (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 9 99.74 Very High Very High Very High
COX-2 inhibitor 6 98.16 Very High Very High Very High
aspirin 6 94.60 High High
dexamethasone 4 92.96 High High
anesthesia 6 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperglycemia 20 97.00 Very High Very High Very High
INFLAMMATION 6 92.04 High High
Flatulence 4 89.12 High High
Diarrhoea 4 88.16 High High
Diabetes Mellitus 68 77.28 Quite High
Toxicity 3 75.00 Quite High
Obesity 24 74.32 Quite High
Body Weight 46 5.00 Very Low Very Low Very Low
Insulin Resistance 12 5.00 Very Low Very Low Very Low
Congenital Anomalies 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These morphological results are consistent with the effects of adrenalectomy on functional development as determined by decreases in sucrase activity and sucrase-isomaltase mRNA expression [14].
Spec (determined) Negative_regulation (decreases) of sucrase
1) Confidence 0.20 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2532488 Disease Relevance 0 Pain Relevance 0
When rats were adrenalectomized (ADX), the activities of sucrase and maltase decreased, and those of lactase and acid ?
Negative_regulation (decreased) of sucrase
2) Confidence 0.20 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2532488 Disease Relevance 0 Pain Relevance 0.09
Treatment with NSAIDs exhibited a decrease in the activity of rat intestinal brush border membrane associated enzymes such as sucrase, lactase, maltase and alkaline phosphatase as compared to the control in the duodenum, jejunum and ileum.
Negative_regulation (decrease) of sucrase in ileum associated with cinod
3) Confidence 0.06 Published 2007 Journal Nutr Hosp Section Abstract Doc Link 17970535 Disease Relevance 0.24 Pain Relevance 0.41
Acabose is a competitive inhibitor of sucrase, glucoamylase, and isomaltase.
Negative_regulation (inhibitor) of sucrase
4) Confidence 0.03 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2809233 Disease Relevance 0.72 Pain Relevance 0
Miglitol is a strong inhibitor of glucoamylase, sucrase, and isomaltase (Goda et al., 2007).
Negative_regulation (inhibitor) of isomaltase
5) Confidence 0.03 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2809233 Disease Relevance 0.71 Pain Relevance 0
Acabose is a competitive inhibitor of sucrase, glucoamylase, and isomaltase.
Negative_regulation (inhibitor) of isomaltase
6) Confidence 0.03 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2809233 Disease Relevance 0.72 Pain Relevance 0
Miglitol is a strong inhibitor of glucoamylase, sucrase, and isomaltase (Goda et al., 2007).
Negative_regulation (inhibitor) of sucrase
7) Confidence 0.03 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2809233 Disease Relevance 0.71 Pain Relevance 0
Treatment with NSAIDs exhibited a decrease in the activity of rat intestinal brush border membrane associated enzymes such as sucrase, lactase, maltase and alkaline phosphatase as compared to the control in the duodenum, jejunum and ileum.
Negative_regulation (decrease) of sucrase in duodenum associated with cinod
8) Confidence 0.02 Published 2007 Journal Nutr Hosp Section Abstract Doc Link 17970535 Disease Relevance 0.24 Pain Relevance 0.41
Treatment with NSAIDs exhibited a decrease in the activity of rat intestinal brush border membrane associated enzymes such as sucrase, lactase, maltase and alkaline phosphatase as compared to the control in the duodenum, jejunum and ileum.
Negative_regulation (decrease) of sucrase in jejunum associated with cinod
9) Confidence 0.02 Published 2007 Journal Nutr Hosp Section Abstract Doc Link 17970535 Disease Relevance 0.24 Pain Relevance 0.41

General Comments

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