INT147575

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ahr, Cyp1a1) response to stress (Ahr, Cyp1a1) mitochondrion (Cyp1a1)
aging (Cyp1a1) DNA binding (Ahr) oxidoreductase activity (Cyp1a1)
Ahr (Mus musculus)
Cyp1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 4 99.22 Very High Very High Very High
Action potential 1 88.92 High High
nMDA receptor 2 87.00 High High
agonist 1 80.32 Quite High
Neurotransmitter 5 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 10 77.68 Quite High
Cytomegalovirus Infection 2 28.08 Quite Low
Neuroblastoma 9 22.24 Low Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Reproductive System Disorders 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ligand-activated AhR binds to the XRE sequence in the promoter region of the CYP1A1 gene to activate its expression [30].
AhR Binding (binds) of CYP1A1
1) Confidence 0.15 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0 Pain Relevance 0
Furthermore, TTX and MK801 differentially affected the association of AhR and its transcriptional co-activator cAMP-responsive-element binding protein with the cytochrome P450 1A1 (cyp1A1) gene enhancer.
AhR Binding (association) of cyp1A1 associated with tetrodotoxin
2) Confidence 0.06 Published 2008 Journal J. Neurochem. Section Abstract Doc Link 17973980 Disease Relevance 0.15 Pain Relevance 0.54

General Comments

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