INT147577

Context Info Confidence 0.05 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0.54

nucleoplasm (ATF4) DNA binding (ATF4) microtubule organizing center (ATF4) cytoplasm (ATF4) nucleus (ATF4) cytoskeleton (ATF4)

ATF4 (Homo sapiens)

Pain Link Frequency Relevance Heat tetrodotoxin 4 99.22 Action potential 1 88.92 nMDA receptor 2 87.00 agonist 1 80.32

Disease Link Frequency Relevance Heat Drug Induced Neurotoxicity 3 77.68

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, TTX and MK801 differentially affected the association of AhR and its transcriptional co-activator cAMP-responsive-element binding protein with the cytochrome P450 1A1 (cyp1A1) gene enhancer.

cAMP-responsive-element binding protein Binding (association) of associated with tetrodotoxin

1) Confidence 0.05 Published 2008 Journal J. Neurochem. Section Abstract Doc Link 17973980 Disease Relevance 0.15 Pain Relevance 0.54

General Comments

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