INT147586

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.54
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Muc1) molecular_function (Muc1) cytoplasm (Muc1)
Anatomy Link Frequency
Schwann cells 4
Muc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 3 98.76 Very High Very High Very High
Disease Link Frequency Relevance Heat
Adhesions 12 99.96 Very High Very High Very High
Recurrence 3 99.92 Very High Very High Very High
Disease 3 99.48 Very High Very High Very High
Pancreatic Cancer 12 99.22 Very High Very High Very High
Pain 3 98.76 Very High Very High Very High
Cancer 3 94.28 High High
Adenocarcinoma 3 92.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MUC1, a type I transmembrane mucin that can affect the adhesive properties of cells, contains a large extracellular tandem repeat domain, which is heavily glycosylated in normal epithelia, but is overexpressed and differentially glycosylated in pancreatic cancer.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of MUC1 associated with pancreatic cancer
1) Confidence 0.43 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.73 Pain Relevance 0.10
Heterotypic adhesion assays between pancreatic cancer cells and Schwann cells revealed that increased expression of MUC1 or MAG enhanced adhesion.
Positive_regulation (increased) of Gene_expression (expression) of MUC1 in Schwann cells associated with pancreatic cancer and adhesions
2) Confidence 0.43 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.90 Pain Relevance 0.06
Heterotypic adhesion assays between pancreatic cancer cells and Schwann cells revealed that increased expression of MUC1 or MAG enhanced adhesion.
Positive_regulation (enhanced) of Gene_expression (expression) of MUC1 in Schwann cells associated with pancreatic cancer and adhesions
3) Confidence 0.43 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.90 Pain Relevance 0.06

General Comments

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