INT147590

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 3.29
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Mag) plasma membrane (Muc1) molecular_function (Muc1)
cytoplasm (Muc1)
Muc1 (Rattus norvegicus)
Mag (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 4 87.84 High High
Disease Link Frequency Relevance Heat
Adhesions 16 98.88 Very High Very High Very High
Pancreatic Cancer 16 98.60 Very High Very High Very High
Adenocarcinoma 4 94.60 High High
Cancer 4 92.40 High High
Pain 4 87.84 High High
Disease 4 87.24 High High
Recurrence 4 86.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion.
MUC1 Binding (receptor) of myelin-associated glycoprotein associated with pancreatic cancer and adhesions
1) Confidence 0.26 Published 2007 Journal Cancer Res. Section Title Doc Link 17974963 Disease Relevance 0.82 Pain Relevance 0.09
We investigated whether MUC1 is a counter-receptor for MAG and if their interaction contributed to pancreatic perineural invasion.
MUC1 Binding (counter-receptor) of MAG
2) Confidence 0.20 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.89 Pain Relevance 0.07
These results support the hypothesis that the adhesive interactions between MUC1 and MAG are of biological significance in pancreatic cancer perineural invasion.
MUC1 Binding (interactions) of MAG associated with pancreatic cancer
3) Confidence 0.19 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.66 Pain Relevance 0
Results showed that MAG binds pancreatic cells expressing MUC1, that this binding is sialidase-sensitive, and that MAG physically associates with MUC1.
MUC1 Binding (associates) of MAG
4) Confidence 0.17 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.91 Pain Relevance 0.07

General Comments

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