INT147635

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD80) intracellular (CD80) cell-cell signaling (CD80)
Anatomy Link Frequency
T-cell 2
CD80 (Homo sapiens)
Pain Link Frequency Relevance Heat
abatacept 15 99.74 Very High Very High Very High
rheumatoid arthritis 6 97.12 Very High Very High Very High
methotrexate 1 95.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 6 97.12 Very High Very High Very High
Disease 1 55.28 Quite High
Infection 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Abatacept selectively modulates the CD80/CD86:CD28 co-stimulatory signal required for full T-cell activation, and has been approved for the treatment of rheumatoid arthritis (RA) in combination with methotrexate in a number of countries, including the United States, Canada, and the European Union.
Regulation (modulates) of Positive_regulation (required) of CD80 in T-cell associated with rheumatoid arthritis, abatacept and methotrexate
1) Confidence 0.44 Published 2007 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 17977488 Disease Relevance 0.38 Pain Relevance 0.53

General Comments

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