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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PLCB1, TRPV1) transport (TRPV1) enzyme binding (PLCB1)
lipid metabolic process (TRPV1) cytoplasm (PLCB1) signal transducer activity (PLCB1)
PLCB1 (Homo sapiens)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 10 99.82 Very High Very High Very High
Inflammation 1 93.92 High High
Spontaneous pain 1 91.80 High High
qutenza 3 90.80 High High
antagonist 2 89.80 High High
Hyperalgesia 5 87.88 High High
dorsal root ganglion 4 83.72 Quite High
agonist 1 78.16 Quite High
Dorsal horn neuron 1 61.76 Quite High
Pain 2 56.60 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 93.92 High High
Pain 3 91.80 High High
Hyperalgesia 5 87.88 High High
Ganglion Cysts 4 83.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sar-SP-induced potentiation of TRPV1 was blocked by inhibition of G-protein, PLCbeta (phospholipase C-beta), or PKC but not by inhibition of PKA (protein kinase A).
PLCbeta Negative_regulation (blocked) of Positive_regulation (potentiation) of TRPV1 associated with substance p
1) Confidence 0.27 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17978048 Disease Relevance 0.92 Pain Relevance 1.62

General Comments

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