INT147679

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.58

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signal transduction (Arrb2) cytoplasmic membrane-bounded vesicle (Arrb2) plasma membrane (Arrb2)
nucleus (Arrb2) intracellular (Arrb2) cytoplasm (Arrb2)
Arrb2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nicotine 5 76.76 Quite High
Opioid 4 76.72 Quite High
transdermal 1 75.92 Quite High
addiction 1 74.96 Quite High
opioid receptor 1 65.32 Quite High
Disease Link Frequency Relevance Heat
Nicotine Addiction 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found an interaction of ARRB2 and OPRM1 genotype on abstinence at 6 months that approached significance; however, interpretation of this finding is limited by the small number of participants with the minor alleles for both genes.
ARRB2 Binding (interaction) of
1) Confidence 0.24 Published 2007 Journal Nicotine Tob. Res. Section Abstract Doc Link 17978999 Disease Relevance 0.22 Pain Relevance 0.58

General Comments

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