INT147823

Context Info Confidence 0.35 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 2.35 Pain Relevance 0.41

cell differentiation (H1fnt) chromosome (H1fnt) nucleus (H1fnt) DNA binding (H1fnt)

Anatomy Link Frequency olfactory nerves 1 H1fnt (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 4 92.00 anesthesia 2 89.76 depression 2 88.56 Paracetamol 2 50.32 headache 5 41.32 Analgesic 4 5.00 corticosteroid 1 5.00 drug abuse 1 5.00 Inflammation 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Disease 5 100.00 Influenza Virus Infection 140 99.92 Attention Deficit Hyperactivity Disorder 1 96.80 Chronic Disease 2 94.84 Staphylococcus Infection 2 90.76 Sprains And Strains 15 90.32 Osteomyelitis 1 89.28 Depression 2 88.56 Vomiting 4 86.08 Lower Respiratory Tract Infection 2 85.88

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

3) of developing complications of presumptive 2009 pandemic influenza A (H1N1) disease (Table 1).

Localization (disease) of H1N1 associated with influenza virus infection and disease

1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2871038 Disease Relevance 0.34 Pain Relevance 0.05

In adults, AEs were reported by 15.8% of H1N1 LAIV recipients and 16.7% of placebo recipients after dose 1 and 7.9% and 7.3% after dose 2 (Supplemental Table S2).

Localization (recipients) of H1N1 LAIV

2) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2966412 Disease Relevance 1.38 Pain Relevance 0.08

Immunohistochemistry demonstrated localization of H1N1 and NP antigens in olfactory nerves and the glomerular layer of the OB.

Localization (localization) of H1N1 in olfactory nerves

3) Confidence 0.18 Published 2007 Journal J. Neurovirol. Section Abstract Doc Link 17994424 Disease Relevance 0.64 Pain Relevance 0.28

General Comments

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