INT147959

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.37
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Dpyd) oxidoreductase activity (Dpyd) cytoplasm (Dpyd)
Anatomy Link Frequency
urine 2
Dpyd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal inflammation 4 100.00 Very High Very High Very High
Eae 42 61.12 Quite High
Pain 10 49.44 Quite Low
backache 2 45.76 Quite Low
shoulder pain 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
noradrenaline 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 6 100.00 Very High Very High Very High
Hypercalcemia 8 99.04 Very High Very High Very High
Disease 1 96.20 Very High Very High Very High
Osteoporosis 25 93.36 High High
Pain 10 49.44 Quite Low
Stress 2 34.32 Quite Low
Increased Venous Pressure Under Development 8 16.00 Low Low
Body Weight 12 5.00 Very Low Very Low Very Low
Reprotox - General 3 8 5.00 Very Low Very Low Very Low
Endometriosis (extended) 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The urinary Dpd level directly reflects bone resorption and is a good index for the following reasons: Dpd is released in association with the decomposition of type I collagen during bone resorption; it is not released at the time of bone formation; the Dpd level is not affected by intake of meals; and Dpd is excreted into the urine without being metabolized.
Neg (without) Localization (excreted) of Dpd in urine associated with hypercalcemia
1) Confidence 0.53 Published 2007 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1810356 Disease Relevance 0.40 Pain Relevance 0.03
The urinary Dpd level directly reflects bone resorption and is a good index for the following reasons: Dpd is released in association with the decomposition of type I collagen during bone resorption; it is not released at the time of bone formation; the Dpd level is not affected by intake of meals; and Dpd is excreted into the urine without being metabolized.
Localization (released) of Dpd in urine associated with hypercalcemia
2) Confidence 0.46 Published 2007 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1810356 Disease Relevance 0.41 Pain Relevance 0
OBJECTIVE: We quantified the total excretion of the collagen crosslinks (CL) pyridinoline (PYD) and deoxypyridinoline (DPD) in 108 ankylosing spondylitis (AS) patients (29 f, 79 m) in correlation to different characteristics of disease to evaluate different mechanism contributing to development of osteoporosis in AS.
Localization (excretion) of DPD associated with spinal inflammation, osteoporosis and disease
3) Confidence 0.17 Published 2007 Journal Eur. J. Med. Res. Section Abstract Doc Link 18024266 Disease Relevance 0.56 Pain Relevance 0.37

General Comments

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