INT147981

Context Info Confidence 0.58 First Reported 2008 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.28 Pain Relevance 0.32

nucleus (Tfdp1) cell cycle (Tfdp1) DNA binding (Tfdp1) transcription factor binding (Tfdp1)

Anatomy Link Frequency ventral 1 Tfdp1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 3 97.28 Spinal cord 2 87.04 allodynia 1 62.92 Hyperalgesia 1 62.36 cytokine 3 25.00 Kinase C 11 5.00 antagonist 11 5.00 adenocard 2 5.00 fibrosis 1 5.00 endometriosis 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 3 97.28 Neuropathic Pain 1 62.92 Hyperalgesia 1 62.36 Endometriosis (extended) 6 5.00 Targeted Disruption 3 5.00 Reprotox - General 1 2 5.00 Intestinal Cancer 2 5.00 Fibrosis 1 5.00 Female Infertility 1 5.00 Alopecia 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We found the PGD2 receptors DP1 and chemoattractant receptor homologous molecule expressed on T helper type 2 cells (CRTH2) localized in neurons of the dorsal, and motoneurons in the ventral horn.

Gene_expression (expressed) of DP1 in ventral

1) Confidence 0.58 Published 2008 Journal J. Neurochem. Section Abstract Doc Link 18028337 Disease Relevance 0.28 Pain Relevance 0.32

For example SAT1 gene expression was enhanced from a 5.9 fold increase to a 7.5 fold increase, whereas cytochrome P450, family 26, subfamily A, polypeptide 1 (CYP26A1) gene expression was repressed from an 18.0 fold increase to a 12.3 fold increase.

Gene_expression (expression) of polypeptide 1

2) Confidence 0.02 Published 2010 Journal Cell Signal Section Body Doc Link PMC2791881 Disease Relevance 0 Pain Relevance 0

General Comments

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