INT148021

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PSD3) intracellular (PSD3) cytoplasm (PSD3)
PSD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
licofelone 7 95.98 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 9 97.28 Very High Very High Very High
Colon Cancer 2 75.00 Quite High
Immunotherapy Of Cancer 2 59.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also present evidences that licofelone was able to affect the arachidonic acid (AA) cascade, as it blocked the activity of 5-LOX and COX enzymes, and it induced, through the phosphorylation of cytoplasmic phospholipase A(2) (cPLA(2)), the release of unesterified AA from HCA-7 membrane phospholipids.
Localization (release) of HCA-7 associated with licofelone
1) Confidence 0.01 Published 2008 Journal Carcinogenesis Section Abstract Doc Link 18033773 Disease Relevance 0.82 Pain Relevance 0.56

General Comments

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