INT148027

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell cycle (Pik3c3) cellular_component (Pik3c3)
Anatomy Link Frequency
neurons 1
Pik3c3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 10 98.92 Very High Very High Very High
vanilloid receptor subtype 1 2 95.20 Very High Very High Very High
dorsal root ganglion 5 94.64 High High
qutenza 11 92.24 High High
Root ganglion neuron 1 75.00 Quite High
antagonist 1 57.20 Quite High
neuropeptide release 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 94.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we compared the pharmacological profile of SP release involved in several intracellular effectors (phosphoinositide 3-kinase (PI3K), Ca2+ release from intracellular stores, and mitogen-activated protein (MAP) kinases) in the presence/absence of extracellular Ca2+ by stimulating DRG neurons with various concentrations (10 to 1,000 nM) of capsaicin.
Localization (release) of phosphoinositide 3-kinase in neurons associated with dorsal root ganglion, qutenza and substance p
1) Confidence 0.24 Published 2008 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 18034335 Disease Relevance 0.34 Pain Relevance 1.17

General Comments

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