INT148090

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 1.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CALCA, NCOR2) nucleoplasm (NCOR2) small molecule metabolic process (NCOR2)
aging (CALCA) intracellular (CALCA) DNA binding (NCOR2)
CALCA (Homo sapiens)
NCOR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 14 100.00 Very High Very High Very High
antagonist 6 98.84 Very High Very High Very High
qutenza 2 91.52 High High
imagery 1 85.68 High High
Migraine 8 79.72 Quite High
headache 3 72.44 Quite High
Neuropeptide 1 61.60 Quite High
Disease Link Frequency Relevance Heat
Migraine Disorders 8 79.72 Quite High
Increased Venous Pressure Under Development 1 73.84 Quite High
Headache 1 70.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, MK-0974 is a potent antagonist of the human (K(i) = 0.77 nM) and rhesus (K(i) = 1.2 nM) CGRP receptors but displays >1500-fold lower affinity for the canine and rat receptors as determined via (125)I-human CGRP competition binding assays.
CGRP Binding (affinity) of receptors associated with antagonist and calcitonin gene-related peptide
1) Confidence 0.00 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18039958 Disease Relevance 0.65 Pain Relevance 1.71

General Comments

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