INT148105

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Context Info
Confidence 0.69
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.86
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (STK24) nucleoplasm (STK24) signal transduction (STK24)
nucleus (STK24) cytoplasm (STK24)
Anatomy Link Frequency
E cells 4
placenta 2
STK24 (Homo sapiens)
Pain Link Frequency Relevance Heat
pain labor 3 96.88 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 27 99.80 Very High Very High Very High
Stress 9 98.10 Very High Very High Very High
Labor Pain 3 96.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The H2O2-induced apoptosis of 3A-sub-E cells was largely suppressed by overexpressed Mst3KR, the kinase-dead mutant or by selective knockdown of endogenous Mst3.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of Mst3KR in E cells associated with apoptosis
1) Confidence 0.69 Published 2008 Journal Apoptosis Section Abstract Doc Link 18040775 Disease Relevance 0.94 Pain Relevance 0.09
The H2O2-induced apoptosis of 3A-sub-E cells was largely suppressed by overexpressed Mst3KR, the kinase-dead mutant or by selective knockdown of endogenous Mst3.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of Mst3 in E cells associated with apoptosis
2) Confidence 0.50 Published 2008 Journal Apoptosis Section Abstract Doc Link 18040775 Disease Relevance 0.95 Pain Relevance 0.09
Oxidative stress, but not hormones released during labor such as prostaglandin E1, oxytocin or angiotensin II, induces the expression of Mst3 and apoptosis of human term placenta after elective Cesarean section without labor pain.
Positive_regulation (induces) of Gene_expression (expression) of Mst3 in placenta associated with stress, pain labor and apoptosis
3) Confidence 0.46 Published 2008 Journal Apoptosis Section Abstract Doc Link 18040775 Disease Relevance 0.96 Pain Relevance 0.10

General Comments

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