INT148264

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SNCA) oxidoreductase activity (SNCA) cell death (SNCA)
extracellular region (SNCA) histone binding (SNCA) plasma membrane (SNCA)
SNCA (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 7 100.00 Very High Very High Very High
Ventral tegmentum 4 75.36 Quite High
Opioid 2 75.00 Quite High
Nucleus accumbens 1 62.40 Quite High
midbrain 2 25.00 Low Low
opiate 1 25.00 Low Low
Kappa opioid receptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Opiate Addiction 4 95.72 Very High Very High Very High
Congenital Anomalies 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We examined mRNA expression levels of DA transporter (DAT), tyrosine hydroxylase (TH), dopamine D2 receptor, alpha-synuclein, and nuclear receptor-related 1 (Nurr1) in discrete mesocorticolimbic and nigrostriatal subpopulations of heroin users and control subjects.
Spec (examined) Transcription (levels) of alpha-synuclein associated with dopamine and opiate addiction
1) Confidence 0.40 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 18057194 Disease Relevance 0.25 Pain Relevance 0.42

General Comments

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