INT148272

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1)
cytoplasm (Nfkb1) cytosol (Nfkb1) signal transduction (Nfkb1)
Anatomy Link Frequency
esophagus 2
Nfkb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 2 75.00 Quite High
cINOD 1 66.24 Quite High
aspirin 1 40.60 Quite Low
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 4 99.28 Very High Very High Very High
Cancer 5 96.72 Very High Very High Very High
Skin Cancer 1 75.00 Quite High
Esophageal Cancer 1 42.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that meloxicam induces apoptosis in SCC of the esophagus in vivo by inhibiting the pathway of NF-kappaB downstream regulation of COX-2.
Negative_regulation (inhibiting) of Regulation (regulation) of NF-kappaB in esophagus associated with apoptosis
1) Confidence 0.04 Published 2008 Journal Int. J. Cancer Section Abstract Doc Link 18058818 Disease Relevance 0.66 Pain Relevance 0.13

General Comments

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