INT148302

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2ry1) aging (P2ry1) plasma membrane (P2ry1)
signal transducer activity (P2ry1)
Anatomy Link Frequency
spinal cord 2
P2ry1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
noradrenaline 4 100.00 Very High Very High Very High
Glutamate 4 100.00 Very High Very High Very High
Analgesic 1 96.96 Very High Very High Very High
Spinal cord 5 95.96 Very High Very High Very High
dorsal root ganglion 1 93.08 High High
medulla 1 89.80 High High
antagonist 3 77.88 Quite High
Neurotransmitter 1 75.00 Quite High
Potency 2 63.84 Quite High
agonist 1 63.52 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 93.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, inhibitory P2Y and facilitatory P2X1-like receptors, involved in the regulation of glutamate (P2Y13 and/or P2Y1) and noradrenaline (P2Y13 and/or P2Y1, P2Y12) release have been identified, which provide novel target sites for analgesics acting at the spinal cord level.
Regulation (involved) of Regulation (regulation) of P2Y1 in spinal cord associated with glutamate, analgesic, noradrenaline and spinal cord
1) Confidence 0.44 Published 2008 Journal Neuropharmacology Section Abstract Doc Link 18063000 Disease Relevance 0.09 Pain Relevance 0.74

General Comments

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