INT148398

Context Info Confidence 0.44 First Reported 2008 Last Reported 2008 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.25

nucleus (BHLHE22)

BHLHE22 (Homo sapiens)

Pain Link Frequency Relevance Heat Clonidine 1 92.20 agonist 4 91.80 Catecholamine 2 58.48

Disease Link Frequency Relevance Heat Pressure Volume 2 Under Development 1 41.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Functional genetic variation in receptor signaling mechanisms, for example in the beta 3 G-protein subunit (GNB3 C825T) and in the alpha(2C)-adrenoceptor subtype (ADRA2C del322-325), may affect drug responses.

Spec (may) Regulation (affect) of beta 3

1) Confidence 0.44 Published 2008 Journal Hypertension Section Abstract Doc Link 18071056 Disease Relevance 0 Pain Relevance 0.25

General Comments

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