INT148430

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) plasma membrane (Snap25) cytoplasm (Snap25)
Anatomy Link Frequency
cerebral cortex 2
Snap25 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Thalamus 1 99.62 Very High Very High Very High
cerebral cortex 1 99.28 Very High Very High Very High
anesthesia 5 97.44 Very High Very High Very High
isoflurane 1 92.88 High High
Versed 1 89.00 High High
Disease Link Frequency Relevance Heat
Body Weight 1 89.96 High High
Apoptosis 1 58.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that this general anesthesia causes permanent neuronal deletion in the most vulnerable brain regions-the cerebral cortex and the thalamus-while transiently modulating protein levels of synaptophysin, synaptobrevin, amphiphysin, SNAP-25, and CaM kinase II.
Regulation (modulating) of Gene_expression (levels) of SNAP-25 in cerebral cortex associated with anesthesia, thalamus and cerebral cortex
1) Confidence 0.27 Published 2007 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 18077565 Disease Relevance 0.15 Pain Relevance 0.53

General Comments

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