INT148448

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) extracellular region (Inhbe)
plasma membrane (Trpv1) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Inhbe (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
Thermal hyperalgesia 2 98.60 Very High Very High Very High
qutenza 3 87.76 High High
Hyperalgesia 1 75.00 Quite High
Root ganglion neuron 1 75.00 Quite High
Pain 1 62.80 Quite High
Stimulus evoked pain 1 51.20 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 3 98.60 Very High Very High Very High
Ganglion Cysts 1 75.00 Quite High
Nociception 2 67.08 Quite High
Pain 2 62.80 Quite High
Injury 1 59.88 Quite High
Hypersensitivity 1 51.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that activin signals through its own receptor, involves PKCepsilon signaling to sensitize the TRPV1 channel, and contributes to acute thermal hyperalgesia.
activin Positive_regulation (sensitize) of TRPV1 associated with thermal hyperalgesia
1) Confidence 0.08 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 18077689 Disease Relevance 0.70 Pain Relevance 0.67

General Comments

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