INT148492

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (Cdk5) cytoplasm (Cdk5) cytosol (Cdk5)
nucleocytoplasmic transport (Cdk5) cell death (Cdk5) nucleolus (Cdk5)
Cdk5 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 2 100.00 Very High Very High Very High
Physical dependence 4 99.84 Very High Very High Very High
tolerance 6 98.86 Very High Very High Very High
Analgesic 7 98.66 Very High Very High Very High
Morphine 6 98.44 Very High Very High Very High
narcan 2 98.14 Very High Very High Very High
analgesia 2 97.12 Very High Very High Very High
Pain 1 92.80 High High
Opioid 1 91.48 High High
withdrawal 2 87.52 High High
Disease Link Frequency Relevance Heat
Drug Dependence 4 99.84 Very High Very High Very High
Pain 1 92.80 High High
Substance Withdrawal Syndrome 1 87.52 High High
Urological Neuroanatomy 2 62.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine-induced analgesic tolerance, locomotor sensitization and physical dependence do not require modification of mu opioid receptor, cdk5 and adenylate cyclase activity.
Neg (not) Positive_regulation (require) of cdk5 Neg (not) Binding (modification) of associated with physical dependence, analgesic, mu opioid receptor, tolerance and morphine
1) Confidence 0.47 Published 2008 Journal Neuropharmacology Section Title Doc Link 18082850 Disease Relevance 0.51 Pain Relevance 1.86

General Comments

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