INT148519

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.74
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (FOS) aging (FOS) nucleolus (FOS)
nucleus (FOS)
Anatomy Link Frequency
ArcN 2
FOS (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 8 100.00 Very High Very High Very High
antinociception 1 93.44 High High
Deafferentation 2 74.60 Quite High
substance P 1 47.60 Quite Low
Glutamate 2 46.56 Quite Low
Inflammation 1 45.20 Quite Low
cytokine 1 44.16 Quite Low
Antinociceptive 1 39.20 Quite Low
midbrain 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 17 100.00 Very High Very High Very High
Pain 4 100.00 Very High Very High Very High
Shock 2 81.84 Quite High
Nociception 1 52.80 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, c-fos transcriptional control involves histone phosphorylation and acetylation which may vary chromatin condensation state, likely leading to changes in nuclear mass, translated into perimeter variations of immunoreactive nuclei (Clayton et al., 2000; Brami-Cherrier et al., 2009).
Regulation (involves) of Regulation (control) of c-fos
1) Confidence 0.44 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2981384 Disease Relevance 0 Pain Relevance 0.04
In the present study, we investigated the differential effects of ES or PS on pain behaviors or on c-Fos immunoreactivity (IR) in the paraventricular nucleus (PVN) or arcuate nucleus (ArcN) using electrical footshock-witness model.
Spec (investigated) Regulation (effects) of Regulation (immunoreactivity) of c-Fos in ArcN associated with stress and pain
2) Confidence 0.26 Published 2008 Journal Brain Res. Section Abstract Doc Link 18086467 Disease Relevance 1.74 Pain Relevance 0.36

General Comments

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