INT148541

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) extracellular region (ST3GAL4)
Golgi apparatus (ST3GAL4) plasma membrane (Trpv1) transmembrane transport (Trpv1)
Anatomy Link Frequency
HEK 2
ST3GAL4 (Homo sapiens)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 94.24 High High
Inflammation 1 77.68 Quite High
qutenza 1 76.12 Quite High
Pain 2 76.00 Quite High
Thermal hyperalgesia 1 75.00 Quite High
Hyperalgesia 1 63.44 Quite High
diabetic neuropathy 3 57.96 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 3 96.40 Very High Very High Very High
Diabetes Mellitus 4 95.24 Very High Very High Very High
Ganglion Cysts 4 94.24 High High
Peripheral Neuropathy 3 57.96 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, in stably TRPV1-expressing HEK 293T cells, STZ treatment induced an increase in TRPV1 protein content and p-p38 MAPK levels, which was abolished with concomitant treatment with catalase or p38 MAPK inhibitor.
STZ Positive_regulation (induced) of Positive_regulation (increase) of TRPV1 protein in HEK
1) Confidence 0.08 Published 2008 Journal Mol. Pharmacol. Section Abstract Doc Link 18089839 Disease Relevance 0.96 Pain Relevance 0.56

General Comments

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