INT148556

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARG, PPARA) DNA binding (PPARG, PPARA) lipid metabolic process (PPARG, PPARA)
nucleus (PPARG, PPARA) small molecule metabolic process (PPARA) enzyme binding (PPARG)
Anatomy Link Frequency
skin 2
PPARG (Homo sapiens)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 99.12 Very High Very High Very High
Inflammation 5 96.92 Very High Very High Very High
psoriasis 3 94.76 High High
Inflammatory response 1 83.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 96.92 Very High Very High Very High
Skin Diseases 4 96.40 Very High Very High Very High
Eczema 3 95.52 Very High Very High Very High
Psoriasis 4 94.76 High High
Dermatitis 1 94.16 High High
Disease 1 75.00 Quite High
Diabetes Mellitus 1 69.68 Quite High
Apoptosis 4 43.20 Quite Low
Malignant Neoplastic Disease 1 38.64 Quite Low
Skin Cancer 6 30.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This observation suggests the possibility that PPARalpha and PPARgamma activators, or compounds that positively regulate PPAR gene expression, may represent novel NSAIDs for the topical or systemic treatment of common inflammatory skin diseases such as atopic dermatitis, psoriasis, and allergic contact dermatitis.
PPARgamma Regulation (regulate) of Gene_expression (expression) of PPAR in skin associated with psoriasis, inflammation, skin diseases, cinod, dermatitis and eczema
1) Confidence 0.30 Published 2008 Journal Am J Clin Dermatol Section Abstract Doc Link 18092840 Disease Relevance 1.20 Pain Relevance 0.31

General Comments

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