INT14871

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.13
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.20
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TGFB3) aging (TGFB3) extracellular region (TGFB3)
plasma membrane (TGFB3) nucleus (TGFB3) embryo development (TGFB3)
Anatomy Link Frequency
chondrocytes 1
TGFB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 11 86.24 High High
alcohol 2 78.36 Quite High
IPN 3 77.24 Quite High
fibrosis 1 70.56 Quite High
Disease Link Frequency Relevance Heat
Pancreatic Cancer 11 96.96 Very High Very High Very High
Pancreatitis 12 86.24 High High
Fibrosis 1 70.56 Quite High
Cancer 7 65.60 Quite High
Disease Progression 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is in vitro evidence that simultaneous overproduction of one of its ligands, transforming growth factor alpha (TGF-alpha), might result in an autocrine loop with an increased proliferation signal.
TGF-alpha Binding (ligands) of
1) Confidence 0.13 Published 1991 Journal J. Pathol. Section Abstract Doc Link 1707959 Disease Relevance 0.53 Pain Relevance 0.16
Cripto is a 188 amino-acid protein containing a central segment that shares amino-acid sequence homology with epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha).
TGF-alpha Binding (homology) of
2) Confidence 0.12 Published 1994 Journal Int. J. Cancer Section Abstract Doc Link 8314343 Disease Relevance 0.66 Pain Relevance 0.32
We conclude from our results, that a combination of TGFbeta3 and BMP2 promotes better differentiation of mesenchymal stem cells to chondrocytes in our scaffold.
TGFbeta3 Binding (combination) of in chondrocytes
3) Confidence 0.00 Published 2010 Journal J Biomed Mater Res A Section Abstract Doc Link 20128001 Disease Relevance 0 Pain Relevance 0.30

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox