INT148713

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HCN4)
HCN4 (Homo sapiens)
Pain Link Frequency Relevance Heat
HCN1 14 100.00 Very High Very High Very High
Potency 4 93.20 High High
Opioid 2 92.56 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The known HCN blocker ZD7288 was also found to be more selective for HCN1 over HCN4, while the HCN blocker DK-AH269 was equipotent on HCN4 and HCN1.
Positive_regulation (selective) of HCN4 associated with hcn1
1) Confidence 0.50 Published 2008 Journal Eur. J. Pharmacol. Section Abstract Doc Link 18162181 Disease Relevance 0 Pain Relevance 0.48
The known HCN blocker ZD7288 was also found to be more selective for HCN1 over HCN4, while the HCN blocker DK-AH269 was equipotent on HCN4 and HCN1.
Positive_regulation (equipotent) of HCN4 associated with hcn1
2) Confidence 0.50 Published 2008 Journal Eur. J. Pharmacol. Section Abstract Doc Link 18162181 Disease Relevance 0 Pain Relevance 0.48

General Comments

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