INT148740

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.58
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp13) extracellular space (Mmp13) extracellular region (Mmp13)
Golgi apparatus (Mmp13) proteinaceous extracellular matrix (Mmp13) lysosome (Mmp13)
Anatomy Link Frequency
articular cartilage 2
Mmp13 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 20 100.00 Very High Very High Very High
Inflammation 2 96.44 Very High Very High Very High
Snapping jaw 8 92.56 High High
Angina 2 65.96 Quite High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 2 99.40 Very High Very High Very High
INFLAMMATION 2 96.44 Very High Very High Very High
Atherosclerotic Plaque 12 95.16 Very High Very High Very High
Osteoarthritis 6 93.44 High High
Temporomandibular Joint Syndrome 8 92.56 High High
Injury 2 75.00 Quite High
Rupture 4 71.72 Quite High
Cv General 3 Under Development 2 65.96 Quite High
Myocardial Infarction 2 65.16 Quite High
Acute Coronary Syndrome 2 63.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the basis of these previous studies, we discuss the need for studies on the effect of statin treatment on the serum levels of MMP-13 and tissue inhibitor of matrix metalloproteinase (TIMP-1) levels in hypercholesterolemic patients.
Regulation (effect) of Gene_expression (levels) of MMP-13 associated with metalloproteinase
1) Confidence 0.03 Published 2008 Journal J Cardiovasc Med (Hagerstown) Section Abstract Doc Link 19001938 Disease Relevance 0.88 Pain Relevance 0.41
However, the effect of statin treatment on the serum levels of MMP-13, which has a critical role in the initiation of collagen degradation, is unknown.
Regulation (effect) of Gene_expression (levels) of MMP-13
2) Confidence 0.03 Published 2008 Journal J Cardiovasc Med (Hagerstown) Section Abstract Doc Link 19001938 Disease Relevance 1.04 Pain Relevance 0.43
Our aim was to examine the change in expression of matrix metalloproteinases (MMP-13), matrix metalloproteinases-3 (MMP-3), and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in the articular cartilage of goats with experimentally-induced osteoarthrosis of the temporomandibular joint (TMJ) at various times.
Spec (examine) Regulation (change) of Spec (examine) Gene_expression (expression) of MMP-13 in articular cartilage associated with snapping jaw, metalloproteinase and osteoarthritis
3) Confidence 0.02 Published 2008 Journal Br J Oral Maxillofac Surg Section Abstract Doc Link 18164790 Disease Relevance 0.66 Pain Relevance 0.52

General Comments

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