INT148788

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 2.14
Pain Relevance 1.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Csk) plasma membrane (Csk) kinase activity (Csk)
cytoplasm (Csk)
Anatomy Link Frequency
sensory neurons 1
Csk (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 2 100.00 Very High Very High Very High
Hyperalgesia 14 99.40 Very High Very High Very High
Mechanotransduction 2 94.96 High High
vincristine 4 87.20 High High
Inflammation 2 87.20 High High
intrathecal 2 82.00 Quite High
Pain 4 81.36 Quite High
qutenza 5 75.00 Quite High
peripheral neuropathy 2 73.64 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 14 99.40 Very High Very High Very High
Targeted Disruption 2 89.16 High High
Diabetes Mellitus 4 87.72 High High
Pain 2 81.36 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 78.96 Quite High
Alcohol Addiction 2 75.76 Quite High
Peripheral Neuropathy 2 73.64 Quite High
Nervous System Injury 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Pathologic Neovascularization 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.
SRC tyrosine kinase Binding (Interaction) of associated with hyperalgesia and nociceptor
1) Confidence 0.12 Published 2008 Journal J. Neurosci. Section Title Doc Link 18234883 Disease Relevance 1.00 Pain Relevance 0.85
Furthermore, we establish a direct interaction between TRPV4, alpha2 integrin, and the Src tyrosine kinase Lyn in sensory neurons.
Src tyrosine kinase Binding (interaction) of in sensory neurons
2) Confidence 0.09 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18234883 Disease Relevance 1.14 Pain Relevance 0.91
In vitro kinase assay and molecular modeling studies revealed that capsiate inhibits Src kinase activity via its preferential docking to the ATP-binding site of Src kinase.
Src kinase Binding (docking) of
3) Confidence 0.05 Published 2008 Journal Cancer Res. Section Abstract Doc Link 18172315 Disease Relevance 0 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox