INT148796

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.66
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
tube 2
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 8 96.08 Very High Very High Very High
Arthritis 2 88.36 High High
qutenza 5 75.00 Quite High
Inflammation 40 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Ziconotide 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 15 99.62 Very High Very High Very High
Cancer 123 89.72 High High
Diabetic Retinopathy 2 89.24 High High
Arthritis 2 88.36 High High
Atherosclerosis 1 87.92 High High
Disease 9 86.96 High High
Stress 2 82.60 Quite High
Pheochromocytoma 1 73.04 Quite High
Carcinoma 6 71.88 Quite High
Hypoxia 4 70.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, capsiate suppressed VEGF-induced activation of Src kinase and phosphorylation of its downstream substrates, such as p125(FAK) and VE-cadherin, without affecting autophosphorylation of the VEGF receptor KDR/Flk-1.
Neg (without) Regulation (affecting) of Phosphorylation (autophosphorylation) of VEGF
1) Confidence 0.35 Published 2008 Journal Cancer Res. Section Abstract Doc Link 18172315 Disease Relevance 0 Pain Relevance 0.14
However, 14,15-EEZE does not affect VEGF-induced phosphorylation of its receptor or FGF-2-stimulated tube formation [115].
Regulation (affect) of Phosphorylation (phosphorylation) of VEGF-induced in tube
2) Confidence 0.09 Published 2010 Journal Cancer Metastasis Rev Section Body Doc Link PMC2962793 Disease Relevance 0.55 Pain Relevance 0.08
In addition, 87 induced apoptosis of HUVECs without affecting their VEGF-induced phosphorylation of ERK1/2 kinases [94].
Neg (without) Regulation (affecting) of Phosphorylation (phosphorylation) of VEGF associated with apoptosis
3) Confidence 0.06 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2852841 Disease Relevance 1.11 Pain Relevance 0.04

General Comments

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