INT148806

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Diablo, Casp3) mitochondrion (Diablo, Casp3) cytoplasm (Diablo, Casp3)
peptidase activity (Casp3) nucleus (Casp3) intracellular (Casp3)
Anatomy Link Frequency
colon 2
Diablo (Mus musculus)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 11 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 6 100.00 Very High Very High Very High
Colon Cancer 3 100.00 Very High Very High Very High
INFLAMMATION 2 75.00 Quite High
Colorectal Cancer 1 69.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Small-molecule SMAC mimetics at nanomolar concentrations significantly sensitize colon cancer cells to NSAID-induced apoptosis by promoting caspase-3 activation and cytochrome c release.
SMAC Positive_regulation (promoting) of Positive_regulation (activation) of caspase-3 in colon associated with colon cancer, cinod and apoptosis
1) Confidence 0.03 Published 2008 Journal Cancer Res. Section Abstract Doc Link 18172320 Disease Relevance 1.02 Pain Relevance 0.89

General Comments

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