INT14885

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Context Info
Confidence 0.67
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.74
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TAC3) extracellular region (TAC3)
TAC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 2 96.88 Very High Very High Very High
Dynorphin 4 80.20 Quite High
Neuropeptide 4 78.60 Quite High
Cholecystokinin 2 69.04 Quite High
Enkephalin 6 68.36 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 10 99.76 Very High Very High Very High
Endometriosis (extended) 1 99.46 Very High Very High Very High
Hypertrophy 3 75.00 Quite High
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data demonstrate that human menopause is associated with marked increases in hypothalamic NKB and SP gene expression.
Positive_regulation (increases) of Gene_expression (expression) of NKB associated with endometriosis (extended)
1) Confidence 0.67 Published 1991 Journal Endocrinology Section Abstract Doc Link 1708331 Disease Relevance 0.17 Pain Relevance 0.17
In contrast, long-term ( approximately 4 yr) OVX significantly increased KiSS-1 and NKB expression, and this was reversed by E(2) administration.
Positive_regulation (increased) of Gene_expression (expression) of NKB
2) Confidence 0.06 Published 2010 Journal Endocrinology Section Abstract Doc Link 20519367 Disease Relevance 0.28 Pain Relevance 0.09
Expression of KiSS-1 and NKB was highly elevated in old perimenopausal compared with young or middle-aged premenopausal animals.
Positive_regulation (elevated) of Gene_expression (Expression) of NKB
3) Confidence 0.06 Published 2010 Journal Endocrinology Section Abstract Doc Link 20519367 Disease Relevance 0.29 Pain Relevance 0.13

General Comments

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