INT14886

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Context Info
Confidence 0.49
First Reported 1991
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.42
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TAC3) extracellular region (TAC3)
Anatomy Link Frequency
hypothalamus 1
TAC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 11 71.08 Quite High
Cholecystokinin 2 69.04 Quite High
Enkephalin 2 68.36 Quite High
agonist 10 66.56 Quite High
Neuropeptide 2 66.56 Quite High
Dynorphin 2 65.28 Quite High
anesthesia 2 50.00 Quite Low
Inflammatory mediators 1 6.92 Low Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis (extended) 2 99.46 Very High Very High Very High
Eclampsia 1 84.36 Quite High
Hypertrophy 3 75.00 Quite High
Reprotox - General 1 1 62.64 Quite High
Increased Venous Pressure Under Development 1 13.20 Low Low
INFLAMMATION 1 6.52 Low Low
Hypogonadotropic Hypogonadism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MEASUREMENTS OR MAIN RESULTS: Patients were randomized to group 1 (n = 49), group 2 (n = 49), or group 3 (n = 58), and received TAC 1, TAC 2, or TAC 3, respectively.
Positive_regulation (received) of TAC 3
1) Confidence 0.49 Published 1996 Journal Arch Pediatr Adolesc Med Section Body Doc Link 8620226 Disease Relevance 0 Pain Relevance 0
These data demonstrate that human menopause is associated with marked increases in hypothalamic NKB and SP gene expression.
Positive_regulation (increases) of NKB associated with endometriosis (extended)
2) Confidence 0.48 Published 1991 Journal Endocrinology Section Abstract Doc Link 1708331 Disease Relevance 0.17 Pain Relevance 0.17
NKB is elevated in the human female hypothalamus after menopause [21].
Positive_regulation (elevated) of NKB in hypothalamus associated with endometriosis (extended)
3) Confidence 0.03 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2724541 Disease Relevance 0.25 Pain Relevance 0.07

General Comments

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