INT148922

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Pdia4) signal transduction (Tnf) extracellular space (Tnf)
extracellular region (Tnf) endoplasmic reticulum (Pdia4) plasma membrane (Tnf)
Pdia4 (Mus musculus)
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 5 98.20 Very High Very High Very High
Arthritis 1 97.08 Very High Very High Very High
Analgesic 4 91.40 High High
Potency 1 75.00 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 2 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
INFLAMMATION 5 98.20 Very High Very High Very High
Arthritis 1 97.08 Very High Very High Very High
Granuloma 1 95.80 Very High Very High Very High
Pressure And Volume Under Development 1 94.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also show that CAI significantly inhibits local vascular permeability stimulated by vascular endothelial growth factor or histamine and decreases tumor necrosis factor-alpha and interleukin-1beta levels at the site of inflammation and in serums, which may contribute to the anti-inflammatory effect.
CAI Negative_regulation (decreases) of tumor necrosis factor-alpha associated with necrosis, inflammation and cancer
1) Confidence 0.09 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18182559 Disease Relevance 1.01 Pain Relevance 0.56

General Comments

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