INT148930

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Rac1, Chrna7) plasma membrane (Rac1, Chrna7) intracellular (Rac1)
enzyme binding (Rac1) GTPase activity (Rac1) cell proliferation (Rac1)
Anatomy Link Frequency
bladder 1
Rac1 (Rattus norvegicus)
Chrna7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Botox 2 100.00 Very High Very High Very High
Neuropeptide 1 99.40 Very High Very High Very High
substance P 1 98.84 Very High Very High Very High
Calcitonin gene-related peptide 1 98.00 Very High Very High Very High
Inflammation 2 90.88 High High
interstitial cystitis 1 87.76 High High
neuropeptide release 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Injury 2 94.56 High High
Cystitis 1 91.84 High High
Neurogenic Inflammation 1 91.32 High High
Urinary Tract Disease 1 88.92 High High
Interstitial Cystitis 1 87.76 High High
INFLAMMATION 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVE: To determine the effect of botulinum toxin type A (BTX-A) on the release of the neuropeptides substance P (SP) and calcitonin gene-related peptide (CGRP) from isolated bladder preparations after acute injury with HCl and the induction of cyclophosphamide (CYP)-induced cystitis, as neurogenic inflammation has been increasingly identified in urological disorders such as interstitial cystitis.
botulinum toxin Spec (determine) Regulation (effect) of BTX in bladder associated with cystitis, calcitonin gene-related peptide, inflammation, neuropeptide, injury, urinary tract disease, interstitial cystitis, neurogenic inflammation, botox and substance p
1) Confidence 0.13 Published 2008 Journal BJU Int. Section Abstract Doc Link 18184328 Disease Relevance 0.60 Pain Relevance 0.44

General Comments

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