INT148932

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Context Info
Confidence 0.79
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.65
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (Calcrl) endosome (Calcrl) endoplasmic reticulum (Calcrl)
plasma membrane (Calcrl) lysosome (Calcrl) signal transducer activity (Calcrl)
Anatomy Link Frequency
sputum 1
spinal trigeminal nucleus 1
Calcrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 32 100.00 Very High Very High Very High
headache 4 97.32 Very High Very High Very High
trigeminal ganglion 2 88.52 High High
Migraine 2 65.28 Quite High
nociceptor 2 25.00 Low Low
Pain 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 6 97.32 Very High Very High Very High
Paralysis 20 90.16 High High
Adult Respiratory Distress Syndrome 30 89.64 High High
Ganglion Cysts 2 88.52 High High
Increased Venous Pressure Under Development 2 87.16 High High
Critical Illness 6 85.76 High High
Pneumonia 8 84.04 Quite High
Cough 2 82.88 Quite High
Atelectasis 4 78.76 Quite High
Nociception 4 66.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, in the trigeminovascular system CGRP receptor localization suggests multiple targets for CGRP in the pathogenesis of primary headaches.
Localization (localization) of CGRP receptor associated with headache and calcitonin gene-related peptide
1) Confidence 0.79 Published 2008 Journal J. Comp. Neurol. Section Abstract Doc Link 18186028 Disease Relevance 0.25 Pain Relevance 0.61
In the spinal trigeminal nucleus, CLR- and RAMP1-ir was localized to "glomerular structures," partly colocalized with CGRP-ir.
Localization (localized) of CLR in spinal trigeminal nucleus associated with calcitonin gene-related peptide
2) Confidence 0.69 Published 2008 Journal J. Comp. Neurol. Section Abstract Doc Link 18186028 Disease Relevance 0.37 Pain Relevance 0.75
The major findings of the study are as follows: (1) blood gases are unaffected by a short period (6 h) of CLR, (2) secretion clearance is enhanced by CLR, and (3) P&PD results in an increase in sputum volume only in patients with excessive secretions.
Localization (secretion) of CLR in sputum
3) Confidence 0.38 Published 2001 Journal Crit Care Section Body Doc Link PMC30713 Disease Relevance 0.71 Pain Relevance 0
We also demonstrated improved secretion clearance in patients during CLR that were unrelated to P&PD.
Localization (secretion) of CLR
4) Confidence 0.38 Published 2001 Journal Crit Care Section Body Doc Link PMC30713 Disease Relevance 0.32 Pain Relevance 0

General Comments

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