INT148964

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Context Info
Confidence 0.77
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 1.59
Pain Relevance 2.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnk18) plasma membrane (Kcnk18)
Anatomy Link Frequency
spinal cord 1
brain 1
Kcnk18 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 21 99.84 Very High Very High Very High
Lamotrigine 12 99.52 Very High Very High Very High
Spinal cord 3 98.80 Very High Very High Very High
agonist 12 98.68 Very High Very High Very High
Glutamate 6 97.00 Very High Very High Very High
Analgesic 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 21 99.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRESK mRNA was highly expressed in DRG compared to brain and spinal cord.
Gene_expression (expressed) of TRESK mRNA in spinal cord associated with dorsal root ganglion and spinal cord
1) Confidence 0.77 Published 2008 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 18190784 Disease Relevance 0.54 Pain Relevance 0.73
In COS-7 cells transfected with mouse TRESK, 30 microM lamotrigine inhibited TRESK by approximately 50%.
Gene_expression (transfected) of TRESK associated with lamotrigine
2) Confidence 0.59 Published 2008 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 18190784 Disease Relevance 0.50 Pain Relevance 0.78
TRESK mRNA was highly expressed in DRG compared to brain and spinal cord.
Gene_expression (expressed) of TRESK mRNA in brain associated with dorsal root ganglion and spinal cord
3) Confidence 0.26 Published 2008 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 18190784 Disease Relevance 0.54 Pain Relevance 0.73

General Comments

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