INT149013
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Here, we describe two of a series of these inhibitors that are potent for TPH activity both in biochemical and cell-based assays. | |||||||||||||||
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Administration of glucocorticoids to rats results in elevations of the tryptophan-metaboliting enzymes and TPH in vivo and that administration of dexamethasone phosphate regulates TDO activity in cells from control and adrenarectomized mice, respectively [38,39]. | |||||||||||||||
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These neurons do not express tryptophan hydroxylase (Tph) or dopa decarboxylase (Aadc), which are required for serotonin synthesis, or the catabolic enzymes monoamine oxidase A and B. | |||||||||||||||
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General Comments
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