INT149108

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Context Info
Confidence 0.67
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.85
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SOD3) mitochondrion (SOD3) extracellular space (SOD3)
oxidoreductase activity (SOD3) extracellular region (SOD3) nucleus (SOD3)
SOD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
diabetic neuropathy 66 99.80 Very High Very High Very High
adenocard 4 93.92 High High
Pain 1 10.00 Low Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
induced neuropathy 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetic Neuropathy 68 99.80 Very High Very High Very High
Stress 14 96.16 Very High Very High Very High
Disease 12 75.44 Quite High
Diabetes Mellitus 40 71.20 Quite High
Neuropathic Pain 14 69.84 Quite High
Alzheimer's Dementia 4 67.12 Quite High
Neurodegenerative Disease 8 61.68 Quite High
Aging 6 60.32 Quite High
Osteoarthritis 5 50.00 Quite Low
Injury 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no correlation of EC-SOD levels with IL-6 as a marker of inflammation in either the comparison group or the OA group.
Gene_expression (levels) of EC-SOD
1) Confidence 0.67 Published 2008 Journal Osteoarthr. Cartil. Section Body Doc Link 18203633 Disease Relevance 0 Pain Relevance 0
Thus, the lower levels of EC-SOD on vascular walls must be positively correlated with a higher risk of progression of oxidative stress in affected patients with the Gly/Gly genotype.
Gene_expression (levels) of EC-SOD associated with stress
2) Confidence 0.56 Published 2001 Journal BMC Med Genet Section Body Doc Link PMC31388 Disease Relevance 0.75 Pain Relevance 0.09
Odds ratios and 95% confidence interval (95% CI) were calculated to assess the strength of the relationship between the Mn-SOD or EC-SOD polymorphisms and DN.


Gene_expression (polymorphisms) of EC-SOD associated with diabetic neuropathy
3) Confidence 0.49 Published 2001 Journal BMC Med Genet Section Body Doc Link PMC31388 Disease Relevance 0.10 Pain Relevance 0.10

General Comments

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